Detalhe da pesquisa
1.
A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy.
Cell
; 178(1): 152-159.e11, 2019 06 27.
Artigo
Inglês
| MEDLINE | ID: mdl-31178121
2.
Pan-KRAS inhibitor disables oncogenic signalling and tumour growth.
Nature
; 619(7968): 160-166, 2023 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-37258666
3.
Diverse alterations associated with resistance to KRAS(G12C) inhibition.
Nature
; 599(7886): 679-683, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34759319
4.
Rapid non-uniform adaptation to conformation-specific KRAS(G12C) inhibition.
Nature
; 577(7790): 421-425, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31915379
5.
Suppressing Nucleotide Exchange to Inhibit KRAS-Mutant Tumors.
Cancer Discov
; 11(1): 17-19, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34003780
6.
The G protein signaling regulator RGS3 enhances the GTPase activity of KRAS.
Science
; 374(6564): 197-201, 2021 Oct 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34618566
7.
Adaptive Resistance to Dual BRAF/MEK Inhibition in BRAF-Driven Tumors through Autocrine FGFR Pathway Activation.
Clin Cancer Res
; 25(23): 7202-7217, 2019 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31515463
8.
Quest for Clinically Effective RAF Dimer Inhibitors.
J Clin Oncol
; 38(19): 2197-2200, 2020 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32432945